MOTS-c Peptide 10mg

Buy MOTS-c Peptide UK: The Mitochondrial Peptide for Metabolic Health & Vitality

MOTS-c Peptide (mitochondrial open reading frame of the 12S rRNA-c) is a groundbreaking 16-amino acid peptide encoded within the mitochondrial genome. Discovered in 2015, this bioactive peptide functions as a mitochondrial-derived signaling molecule that bridges cellular energy production with systemic metabolic regulation.

Mechanism of Action

MOTS-c primarily activates the AMPK pathway, the body’s master energy sensor. It inhibits the folate cycle, leading to AICAR accumulation—an endogenous AMPK activator that promotes glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. This mechanism enhances insulin sensitivity and metabolic flexibility under energy stress conditions.

What is MOTS-c Peptide UK?

MOTS-c is a key subject in metabolic and aging research due to its localized and systemic regulatory roles. While most cellular instructions come from the nucleus, it demonstrates the mitochondria’s ability to actively control metabolic pathways in response to cellular stress.

• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

• Origin: Encoded within the mitochondrial DNA (12S rRNA).

• Primary Mechanism: Activation of the AMPK (AMP-activated protein kinase) pathway, the body’s “master metabolic switch.”

Key Benefits

· Metabolic Optimization: MOTS-c improves glucose utilization and lipid metabolism, making it a promising agent for addressing obesity, insulin resistance, and type 2 diabetes. Studies show it can prevent diet-induced obesity and reduce blood glucose levels.
· Anti-Aging Support: Circulating MOTS-c levels decline with age—by up to 21% in older adults—correlating with increased risk of age-related diseases. The peptide helps preserve mitochondrial function, reduce oxidative stress, and combat chronic inflammation.
· Exercise Performance & Muscle Health: Known as an “exercise mimetic,” MOTS-c enhances physical endurance, prevents age-related muscle loss (sarcopenia), and supports muscle mass maintenance.
· Neuroprotection: The peptide crosses the blood-brain barrier and exhibits neuroprotective properties, with potential applications in neurodegenerative conditions.

With a molecular weight of 2174.59 Da and a purity exceeding 97%, MOTS-c represents a cutting-edge research tool for exploring mitochondrial signaling, metabolic disorders, and healthy aging.

How Does MOTS-c peptide Regulate Metabolism?

In preclinical laboratory models, it is studied for its ability to restore metabolic homeostasis by simulating the effects of exercise and caloric restriction at a molecular level.

• AMPK Activation: Researching how peptide increases glucose uptake in muscle tissue and enhances fatty acid oxidation.

• Mitochondrial Homeostasis: Studying the peptide’s role in maintaining the integrity and efficiency of the mitochondrial network under oxidative stress.

• Stress Adaptation: Investigating how it signals the nucleus to upregulate protective genes during periods of metabolic demand or environmental stress.

Primary Research Applications

Because of its role as a systemic metabolic regulator, it is a leader among peptides for sale for several diverse fields of study:

• Aging & Longevity Research: Investigating how MOTS-c levels decline with age and the impact of its restoration on cellular senescence.

• Metabolic Flexibility: Studying the peptide’s influence on insulin sensitivity and lipid metabolism in animal models of obesity.

• Exercise Mimicry: Researching the molecular pathways through which MOTS-c replicates the systemic benefits of physical activity.

• Proteostasis & Cellular Health: Observing the impact of mitokines on protein folding and the prevention of cellular degradation.

Why Choose the Peptide Sciences Labs?

In a competitive research landscape, the purity of your mitochondrial analogs is non-negotiable. PeptideScience ensures your data is supported by the highest quality reagents available.

• Verified 99%+ Purity: Every 10mg vial of MOTS-c is tested via HPLC-MS to ensure sequence accuracy and chemical stability.

• Full Lab Transparency: We provide a Certificate of Analysis (COA) with every batch for your laboratory’s quality assurance records.

• Secure & Discreet Shipping: We prioritize professional logistics to ensure your research materials arrive securely and on time.

• Bulk Laboratory Savings: Use an official Peptide Sciences coupon at checkout for competitive pricing on high-volume research orders.

Note: MOTS-c Peptide is provided for Laboratory Research Use Only. It is not intended for human or animal consumption. Please ensure all safety and handling protocols are strictly followed in your facility.